DDR5 needs a new motherboard, not a BIOS tweak.

You can’t just swap DDR4 for DDR5 on the same board. The slots are physically different, and the memory controller is built into the CPU—so the motherboard and CPU have to support one or the other. There’s no consumer board that runs both.

If you’re building a new PC with a DDR5 motherboard, it’s plug-and-play in the sense that it will boot at default speeds. But you’ll want to enable XMP (Intel) or EXPO (AMD) in the BIOS to get the rated speed and timings—otherwise it runs at a safe JEDEC baseline like 4800MHz. That’s true for DDR4 too.

If you’re trying to upgrade an existing DDR4 system to DDR5, you need a new motherboard and probably a new CPU. That’s a rebuild, not a setting.

Double-check compatibility before buying.