You might want a slightly bigger pad.
Yes, but not because of the grip angle itself—it’s more about how you move the mouse. With a vertical mouse, your wrist stays in a neutral handshake position, so you tend to move from your forearm and elbow rather than flicking your wrist. That natural arc across the desk needs a little extra real estate.
A standard 9x7 inch mousepad often feels cramped. Most people end up bumping the edge or lifting to recenter. A medium-sized pad—say 12x10—gives you room to slide without thinking about it.
You don’t need a giant desk mat, but the cheap freebie pad that came with your computer probably won’t cut it. Spend the $15. Your shoulder will thank you.
